Galleria mellonella immune-relevant proteins and peptides

  • Meltem Erdem Küçük Zonguldak Bülent Ecevit Üniversitesi Ahmet Erdoğan SHMYO Tıbbi Hizmetler ve Teknikler Bölümü
  • Ayşe Kaplan
Keywords: defense proteins and peptides, Galleria mellonella


There is an increasing number of reports concerning identification of Galleria mellonella immune-relevant peptides and proteins. The large wax moth Galleria mellonella, which is used as a model organism in various fields of medicine and biology, belongs to the order of Lepidoptera. Most of these studies are related to proteins and peptides involved in insect immune system. This review article discusses the properties of the most well-known defense proteins and peptides in the immune response of G. mellonella, which are used in infection studies.