INVESTIGATION OF ANTIMICROBIAL AND ANTIBIOFILM EFFECTS OF Ginkgo biloba L.

Funda Karakaya; Birgütay Şahin; Ali Savaş Bülbül; Yusuf Ceylan; Elifnur Kurt; Mehmet Faruk Tarakçı

Funda Karakaya
Birgütay Şahin
Ali Savaş Bülbül Kahramanmaraş Sütçü İmam University, Faculty of Science and Letters, Department of Biology, Kahramanmaraş
Yusuf Ceylan
Elifnur Kurt
Mehmet Faruk Tarakçı

Keywords: Gingko biloba, Antimicrobial activity, Antibiofilm, Plant extract

Abstract

Plants have been used to cure many diseases from past to present and are also used for industrial and medical purposes today. Plants are very essential in Turkey as in all countries. In our country which is rich in plant types, various methods are used to make use of plants especially medically. In this study, it was aimed to analyze antimicrobial and antibiofilm activity of Ginkgo biloba extract. Leaves were extracted with three different solvents like water, methanol and chloroform to analyze antimicrobial activity of the extracts. In vitro antimicrobial effects of extracts were investigated using disc diffusion method. The effects of plant extracts against Enterobacter aerogenes ATCC 13048, Salmonella infantis, Listeria monocytogenes, Klebsiella pnemoniae, Listeria innocua, Salmonella enteritidis ATCC 13075, Enterococcus durans, Salmonella typhimurium, Staphylococcus epidermidis DSMZ 20044, Escherichia coli ATCC 259222, Staphylococcus aureus ATCC 25923, Bacillus subtilis antimicrobial and antibiofilm formation against gram positive and gram negative bacteria were examined. The plant extracts dissolved in different solvent inhibited bacterial growth at different rates. Methanol extract has been shown strong activity against both gram-positive and gram-negative bacteria. There is no any effect in the antibiofilm test.